TOSS meat with Dry Rubs; place in slow cooker. Add all remaining ingredients except flour and water; stir gently. Cover with lid.
COOK on LOW 8 to 9 hours (or on HIGH 4 to 5 hours).
MIX flour and water until blended. Add to slow cooker; mix well. Cook, covered, on HIGH 15 min. or until sauce is slightly thickened.